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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Duloxetine
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Treat depression, anxiety, nerve pain
MDD, GAD, Neuropathic pain, Fibromyalgia
30-60 mg daily
Approved for GAD (>=7 yrs)
Start low
120 mg/day
Avoid if CrCl < 30
Avoid in hepatic impairment
Nausea, dry mouth, somnolence
Hepatotoxicity, suicidal thoughts
MAOI use, uncontrolled narrow-angle glaucoma
Risk of suicidality in children/young adults
MAOIs, SSRIs, CYP1A2 inhibitors
N/A
Heavy alcohol use increases liver injury risk
Risk of neonatal complications
Use caution
Swallow whole, do not crush or chew
Skip missed dose
Mood changes, blood pressure
Content for Duloxetine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.