Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographRxClass: SSRI

Fluoxetine

Generic Name: Fluoxetine

Common Brand Names: Prozac
Dosage Form:Capsule
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Treat depression, OCD, panic disorder

Medical Conditions Treated:

MDD, OCD, Bulimia nervosa, Panic disorder

Dosage & Administration Guidelines

Adult Dosage

20-60 mg daily

Pediatric Dosage

10-20 mg daily (>=8 yrs)

Elderly / Geriatric Considerations

Consider lower starting dose

Maximum Dose Limit

80 mg/day

Renal Impairment:

No adjustment needed

Hepatic Impairment:

Use lower or less frequent dose

Side Effects & Safety Warnings

Common Side Effects

Insomnia, nausea, anorexia

Serious Adverse Reactions

Serotonin syndrome, suicidal thoughts

Contraindications:

MAOI use

Important Warnings & Precautions:

Long half-life requires 5 week washout for MAOIs

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

MAOIs, NSAIDs, CYP2D6 substrates

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

Avoid

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Risk in third trimester

Breastfeeding / Lactation

Not recommended

Patient Counseling & Practical Advice

How to Take:

Take in the morning

What to Do if You Miss a Dose:

Take as soon as remembered

Recommended Monitoring & Lab Tests:

Mood changes, suicidality

Related Medicines in SSRI

Trustworthy Sources & Medical Review

Content for Fluoxetine was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.