Hydrochlorothiazide
Generic Name: Hydrochlorothiazide
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Hypertension, edema
High blood pressure, fluid retention
Dosage & Administration Guidelines
12.5-50 mg daily
1-2 mg/kg/day
Start at 12.5 mg
50 mg/day
Ineffective if CrCl < 30 mL/min
Use with caution
Side Effects & Safety Warnings
Increased urination, hypokalemia, dizziness
Hyponatremia, gout exacerbation, hypercalcemia
Anuria, sulfonamide allergy
Monitor electrolytes
Interactions (Drugs, Food & Alcohol)
Lithium, NSAIDs
N/A
Increased orthostatic hypotension
Pregnancy & Breastfeeding Safety
Use with caution
Compatible but may decrease milk supply
Patient Counseling & Practical Advice
Take in the morning to avoid nocturia
Take as soon as remembered, skip if late in the day
BP, serum electrolytes
Content for Hydrochlorothiazide was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.