Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescriptionClass: Beta-Blockers, Cardioselective

Metoprolol

Generic Name: Metoprolol Succinate / Metoprolol Tartrate

Common Brand Names: Lopressor, Toprol-XL
Dosage Form:Tablet, ER Tablet, Injection
Route:Oral, Intravenous
Pregnancy Category:C
Last Reviewed:9/6/2026

Seek Urgent Medical Attention If:

Severe dizziness, fainting, crushing chest pain, extreme shortness of breath with pink frothy sputum.

Uses & Medical Indications

Treatment of hypertension, angina pectoris, and heart failure

Medical Conditions Treated:

Hypertension, Angina, Heart Failure, Myocardial Infarction

Dosage & Administration Guidelines

Adult Dosage

50-100 mg daily in single or divided doses

Pediatric Dosage

1-2 mg/kg/day orally (Off-label)

Elderly / Geriatric Considerations

Start at lower end of dosing range

Maximum Dose Limit

400 mg/day

Renal Impairment:

No adjustment necessary

Hepatic Impairment:

Consider dose reduction in severe hepatic impairment

Side Effects & Safety Warnings

Common Side Effects

Dizziness, fatigue, depression, bradycardia, diarrhea

Serious Adverse Reactions

Heart block, bronchospasm, heart failure exacerbation

Contraindications:

Severe bradycardia, heart block greater than first degree, cardiogenic shock

Important Warnings & Precautions:

Avoid abrupt cessation (taper over 1-2 weeks). May mask hypoglycemia symptoms.

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Calcium channel blockers (diltiazem, verapamil), digoxin, amiodarone

Food & Dietary Interactions:

Take with or immediately following meals

Alcohol Interaction Warning:

May increase hypotensive effects

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use if benefits outweigh risks; monitor neonate for bradycardia and hypoglycemia

Breastfeeding / Lactation

Excreted in breast milk; observe infant for bradycardia

Patient Counseling & Practical Advice

How to Take:

Do not stop abruptly. Arise slowly to avoid dizziness. Take with food.

What to Do if You Miss a Dose:

Take as soon as remembered; skip if next dose is within 8 hours (ER) or 4 hours (IR)

Recommended Monitoring & Lab Tests:

Blood pressure, heart rate, ECG

Frequently Asked Questions

Trustworthy Sources & Medical Review

Content for Metoprolol was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • AHA / ACC / Heart Failure Society of AmericaGuideline for the Management of Heart Failure
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/6/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.