Pregabalin
Generic Name: Pregabalin
Seek Urgent Medical Attention If:
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Uses & Medical Indications
Neuropathic pain, postherpetic neuralgia, fibromyalgia, partial onset seizures
Fibromyalgia, Diabetic Peripheral Neuropathy, Postherpetic Neuralgia
Dosage & Administration Guidelines
50-75 mg twice daily, increase to 150 mg twice daily
Based on weight for partial onset seizures (1 month and older)
Adjust based on renal function
600 mg/day
Dose reduction required if CrCl < 60 mL/min
No adjustment necessary
Side Effects & Safety Warnings
Dizziness, somnolence, peripheral edema, weight gain, dry mouth
Angioedema, suicidal thoughts, respiratory depression (with CNS depressants)
Hypersensitivity to pregabalin
Taper gradually to avoid withdrawal seizures or symptoms
Interactions (Drugs, Food & Alcohol)
CNS depressants, opioids, pioglitazone/rosiglitazone (fluid retention)
N/A
Increases CNS depression
Pregnancy & Breastfeeding Safety
Use only if benefit outweighs risk
Present in human milk; use caution
Patient Counseling & Practical Advice
Do not stop abruptly. May cause drowsiness or dizziness.
Take as soon as remembered. Skip if near next dose.
Renal function, mood changes, edema, weight
Content for Pregabalin was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
- Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
- World Health Organization (WHO) — Model List of Essential Medicines 23rd List
- Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
- National Health Service (NHS) — Medicines A to Z Clinical Guidelines
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.