Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescriptionClass: HMG-CoA Reductase Inhibitors (Statins)

Rosuvastatin

Generic Name: Rosuvastatin

Common Brand Names: Crestor, Ezallor Sprinkle
Dosage Form:Tablet, Capsule
Route:Oral
Pregnancy Category:X
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Reduce LDL cholesterol, triglycerides, increase HDL, slow progression of atherosclerosis

Medical Conditions Treated:

Hyperlipidemia, Prevention of Cardiovascular Disease

Dosage & Administration Guidelines

Adult Dosage

5-40 mg once daily

Pediatric Dosage

5-20 mg daily for heterozygous familial hypercholesterolemia (>= 8 yrs)

Elderly / Geriatric Considerations

Start at 5 mg daily

Maximum Dose Limit

40 mg/day (only for severe hypercholesterolemia)

Renal Impairment:

Start at 5 mg daily; max 10 mg/day if CrCl < 30 mL/min

Hepatic Impairment:

Contraindicated in active liver disease

Side Effects & Safety Warnings

Common Side Effects

Myalgia, headache, abdominal pain, nausea, asthenia

Serious Adverse Reactions

Rhabdomyolysis, hepatotoxicity, immune-mediated necrotizing myopathy

Contraindications:

Active liver disease, pregnancy, lactation

Important Warnings & Precautions:

Increased risk of myopathy/rhabdomyolysis in elderly or with interacting drugs

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Cyclosporine, gemfibrozil, protease inhibitors, warfarin

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

Heavy use increases risk of liver damage

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Contraindicated in pregnancy

Breastfeeding / Lactation

Contraindicated during breastfeeding

Patient Counseling & Practical Advice

How to Take:

Report unexplained muscle pain, tenderness, or weakness immediately.

What to Do if You Miss a Dose:

Take as soon as remembered. Skip if more than 12 hours late.

Recommended Monitoring & Lab Tests:

Lipid panel, CPK (if muscle symptoms), LFTs

Trustworthy Sources & Medical Review

Content for Rosuvastatin was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.