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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Sertraline
High fever, intense shivering, confusion, rigid muscles, rapid heart rate, dilated pupils (signs of Serotonin Syndrome).
MDD, OCD, panic disorder, PTSD, PMDD, social anxiety disorder
Major Depressive Disorder, OCD, Panic Disorder, PTSD
50 mg once daily (for most indications)
25 mg once daily for OCD (6-12 years)
Start at 25 mg once daily
200 mg/day
No adjustment necessary
Lower dose or less frequent dosing in hepatic impairment
Nausea, diarrhea, insomnia, dizziness, sexual dysfunction
Suicidal thoughts, serotonin syndrome, increased bleeding risk, hyponatremia
Use with MAOIs, pimozide
Increased risk of suicidality in children/young adults
MAOIs, NSAIDs, other serotonergic agents, pimozide
N/A
Avoid alcohol
High risk of Serotonin Syndrome (hyperthermia, neuromuscular hyperactivity, autonomic instability).
Generally preferred SSRI in pregnancy and breastfeeding, though risks exist
Present in human milk in very low amounts; often considered SSRI of choice
May take 4-6 weeks to work. Report worsening depression.
Take as soon as remembered. Skip if near next dose.
Mood changes, suicidality, growth in children
Content for Sertraline was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.