Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescription OnlyClass: P2Y12 Platelet Inhibitors

Ticagrelor

Generic Name: Ticagrelor

Common Brand Names: Brilinta
Dosage Form:Tablet
Route:Oral
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

To reduce the rate of cardiovascular death, MI, and stroke in patients with acute coronary syndrome (ACS) or a history of MI

Medical Conditions Treated:

Acute Coronary Syndrome, History of Myocardial Infarction

Dosage & Administration Guidelines

Adult Dosage

180 mg loading dose, then 90 mg twice daily for 1 year, then 60 mg twice daily

Pediatric Dosage

Not established

Elderly / Geriatric Considerations

No dosage adjustment needed

Maximum Dose Limit

90 mg twice daily

Renal Impairment:

No adjustment necessary

Hepatic Impairment:

Avoid in severe hepatic impairment

Side Effects & Safety Warnings

Common Side Effects

Bleeding, dyspnea

Serious Adverse Reactions

Major bleeding, intracranial hemorrhage, bradycardia

Contraindications:

History of intracranial hemorrhage, active pathological bleeding

Important Warnings & Precautions:

Aspirin maintenance dose should not exceed 100 mg/day

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Strong CYP3A4 inhibitors and inducers, aspirin > 100mg

Food & Dietary Interactions:

Grapefruit juice may increase levels

Alcohol Interaction Warning:

Avoid excessive use (increased bleeding risk)

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use only if benefit justifies risk

Breastfeeding / Lactation

Not recommended

Patient Counseling & Practical Advice

How to Take:

Do not take more than 100mg of aspirin daily. Report any unusual bleeding. May cause shortness of breath.

What to Do if You Miss a Dose:

Skip the missed dose and take the next dose at the scheduled time.

Recommended Monitoring & Lab Tests:

Signs of bleeding, dyspnea, hemoglobin

Trustworthy Sources & Medical Review

Content for Ticagrelor was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.