Trusted, medically reviewed health information • Not a substitute for medical advice
Medically Verified MonographPrescription OnlyClass: Anticholinergics (LAMA)

Tiotropium

Generic Name: Tiotropium

Common Brand Names: Spiriva HandiHaler, Spiriva Respimat
Dosage Form:Inhalation Powder, Inhalation Spray
Route:Inhalation
Pregnancy Category:C
Last Reviewed:9/21/2026

Seek Urgent Medical Attention If:

You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.

Uses & Medical Indications

Maintenance treatment of COPD and Asthma

Medical Conditions Treated:

COPD, Asthma

Dosage & Administration Guidelines

Adult Dosage

18 mcg (1 capsule) inhaled once daily OR 2 actuations once daily

Pediatric Dosage

Asthma: 2 actuations of 1.25 mcg once daily (6 years and older)

Elderly / Geriatric Considerations

No dosage adjustment needed

Maximum Dose Limit

1 capsule/day OR 2 actuations/day

Renal Impairment:

Monitor closely in moderate to severe renal impairment (CrCl < 60 mL/min)

Hepatic Impairment:

No adjustment necessary

Side Effects & Safety Warnings

Common Side Effects

Dry mouth, upper respiratory tract infection, pharyngitis, cough

Serious Adverse Reactions

Paradoxical bronchospasm, acute narrow-angle glaucoma, worsening urinary retention

Contraindications:

Hypersensitivity to tiotropium or ipratropium

Important Warnings & Precautions:

Not for relief of acute bronchospasm

Interactions (Drugs, Food & Alcohol)

Drug-Drug Interactions:

Other anticholinergic medications

Food & Dietary Interactions:

N/A

Alcohol Interaction Warning:

N/A

Pregnancy & Breastfeeding Safety

Pregnancy Safety

Use only if benefit outweighs risk

Breastfeeding / Lactation

Use caution

Patient Counseling & Practical Advice

How to Take:

Do not swallow capsules. Use at the same time each day. May cause dry mouth.

What to Do if You Miss a Dose:

Take as soon as remembered. Do not take more than one dose every 24 hours.

Recommended Monitoring & Lab Tests:

Lung function (FEV1), signs of anticholinergic toxicity

Trustworthy Sources & Medical Review

Content for Tiotropium was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:

  • Central Drugs Standard Control Organization (CDSCO) — National List of Essential Medicines
  • World Health Organization (WHO) — Model List of Essential Medicines 23rd List
  • Indian Pharmacopoeia Commission (IPC) — Indian Pharmacopoeia Drug Monographs
  • National Health Service (NHS) — Medicines A to Z Clinical Guidelines
Reviewer Credentials: PharmD, Clinical PharmacologistLast Reviewed Date: 9/21/2026

The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.