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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Ursodiol
You experience severe allergic reaction symptoms (swelling of the face, lips, tongue, or throat causing difficulty breathing), severe rash with skin peeling, sudden intense chest pain, or symptoms of overdose. Call emergency medical services immediately.
Dissolution of radiolucent gallstones; prevention of gallstones; treatment of primary biliary cholangitis (PBC)
Gallstones, Primary Biliary Cholangitis
Gallstones: 8-10 mg/kg/day in 2-3 divided doses. PBC: 13-15 mg/kg/day in 2-4 divided doses.
PBC: 13-15 mg/kg/day
No specific adjustments
Based on weight
No adjustment required
Contraindicated in complications of liver disease requiring surgery
Diarrhea, headache, dizziness, dyspepsia
Worsening of liver function in some patients, cholecystitis
Calcified cholesterol stones, radio-opaque stones, acute cholecystitis
Monitor for abnormal liver tests. Not for treatment of acute cholecystitis.
Bile acid sequestrants, aluminum-based antacids, oral contraceptives
N/A
N/A
Generally considered safe if needed
Present in human milk in small amounts, likely safe
Take with food. Do not chew tablets. May take months for gallstones to dissolve.
Take as soon as remembered. Skip if close to next dose.
Liver function tests (AST, ALT, GGT, Alk Phos, Bilirubin), ultrasound of gallbladder
Content for Ursodiol was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.