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Trusted, medically reviewed health information • Not a substitute for medical advice
Important: The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Generic Name: Omeprazole
Vomiting blood or coffee-ground emesis, black tarry stools, sudden severe chest/epigastric pain.
Treatment of GERD, peptic ulcer disease, erosive esophagitis
GERD, Erosive Esophagitis, Zollinger-Ellison Syndrome, H. pylori eradication
20-40 mg once daily before a meal
Weight-based dosing (e.g., 10-20 mg once daily)
Same as adult
120 mg/day (Zollinger-Ellison)
No adjustment necessary
Reduce dose to 10-20 mg daily in severe hepatic impairment
Headache, abdominal pain, nausea, diarrhea, flatulence
C. difficile-associated diarrhea, bone fractures, hypomagnesemia, acute interstitial nephritis
Hypersensitivity to omeprazole or other PPIs, use with rilpivirine
Increased risk of fractures and C. difficile diarrhea with long-term use
Clopidogrel, ketoconazole, digoxin, methotrexate
Take 30-60 minutes before a meal
May worsen GERD symptoms
Significant reduction in the antiplatelet efficacy of Clopidogrel, elevating risk of recurrent cardiovascular events.
Use if benefits outweigh risks
Present in breast milk; consider risks vs benefits
Take 30 minutes before breakfast. Swallow whole; do not crush or chew.
Take as soon as remembered. Skip if near next dose.
Resolution of GI symptoms, magnesium levels (if long-term)
Content for Omeprazole was synthesized and fact-checked against standardized regulatory monographs, official pharmacopoeias, and national health authorities:
The information provided on this website is for educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.